Job location: Medical School-Johnson Pavilion
The Research Investigator Sr (SRI) will act in a leadership role, overseeing and designing advanced experiments. He/She will assist the Principal Investigator and play a leading role in developing a research program in the advancement of specific area of study and will play a crucial role both in all aspects of research products including development, implementation, and data analysis. In the development stage, the SRI will assess proposed projects by conducting feasibility studies to provide valuable input regarding viability, efficiency, timeline, and study design. In the implementation stage, he/she will supervise and perform the project. This includes overseeing workflow and productivity of lab personnel and providing training to them on specific techniques as necessary. Finally, the SRI will be responsible for data analysis, preparation of manuscripts, and presenting research findings through various forums. Senior Research Investigator must demonstrate the ability to analyze and present data in professional "publication ready" format and to be able to independently prepare manuscripts and grant writings for submission.
The person holding this position will direct and oversee projects exploring the role of type I interferons in HIV, SIV and SHIV natural history. The person should have at least 5-10 years of experience in standard molecular biology techniques, HIV/SIV/SHIV virus isolation, human and non-human primate primary cells tissue culture, and a broad knowledge of innate and adaptive immunity, in particular of type I interferons. The person should be familiar with HIV/SIV/SHIV culture under BSL2/3 containment condition, be able to perform viral neutralization assays in primary and reporter cell-lines, clone full-length replication competent genomes of HIV/SIV/SHIV, perform site-directed mutagenesis, and analyze next generating sequencing data. Proficiency in DNA/RNA extraction, PCR protocols including Single Genome Amplification, and next generation sequencing library preparation is required.
Job Qualifications:
Ph.D., MD or equivalent doctoral degree and 5 years of experience required.
Position contingent upon funding.
Job Location - City, StatePhiladelphia, PennsylvaniaDepartment / SchoolPerelman School of MedicinePay Range$35,568.00 - $204,000.00Affirmative Action Statement
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