Principal Research Associate, Next-Generation Analytics
ModernaTX, Inc.

Cambridge, Massachusetts

Posted in Science and Research

Job Info

The Role:

Moderna is seeking an internally motivated Principal Research Associate to join our Next Generation Analytics (NGA) team. The primary focus for this lab position is to leverage Next-Generation Sequencing (NGS), NanoString, qPCR, and other emerging sequencing platforms to analyze RNA and DNA samples in support of Moderna's mission to develop mRNA therapeutics. The successful candidate will work with groups across the company to develop and execute state-of-the-art sequencing protocols. The candidate should have a strong background in molecular biology. Applicants should be collaborative, detail oriented, and unafraid to take charge to creatively solve challenges.

Here's What You'll Do:

  • Independently research and optimize emerging wet lab 10x Genomics single cell NGS based protocols including but not limited to: scRNAseq, CITE-seq, single cell ATAC, and analysis of CRISPR clones.
  • Mentor associates within the group on novel and more traditional sequencing assays within the lab.
  • Review data generated by associates within group and provide feedback and troubleshooting guidance.
  • Play a central role in the critical analysis and interpretation of results.
  • Collaborate, lead, and interact regularly with cross-functional groups to troubleshoot and resolve complex technical problems to deliver data against aggressive timelines.
  • Identify and independently execute on new opportunities to expand sequencing capabilities.
  • Contribute to core offerings of group as needed.

Here's What You'll Bring to the Table:
  • An MS with 2-5 years of industry experience in Biology, Biochemistry, Molecular Biology, Genetics, or related science
  • Hands on experience in Next-Generation Sequencing as well as molecular biology
  • Demonstrated experience using Illumina, 10x Genomics, Nanopore, NanoString, and qPCR instruments
  • Extensive understanding of RNA and DNA sequencing methodologies
  • Commitment to excellence and innovation
  • Effective time management and planning skills
  • Self-starter, strong communicator, and team player

Moderna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including:
  • Highly competitive and inclusive medical, dental and vision coverage options
  • Flexible Spending Accounts for medical expenses and dependent care expenses
  • Lifestyle Spending Account funds to help you engage in personal enrichment and self-care activities
  • Family care benefits, including subsidized back-up care options and on-demand tutoring
  • Free premium access to fitness, nutrition, and mindfulness classes
  • Exclusive preferred pricing on Peloton fitness equipment
  • Adoption and family-planning benefits
  • Dedicated care coordination support for our LGBTQ+ community
  • Generous paid time off, including:
    • Vacation, sick time and holidays
    • Volunteer time to participate within your community
    • Discretionary winter shut down
    • Paid sabbatical after 5 years; every 3 years thereafter
  • Generous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents
  • 401k match and Financial Planning tools
  • Moderna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit options
  • Complimentary concierge service including home services research, travel booking, and entertainment requests
  • Free parking or subsidized commuter passes
  • Location-specific perks and extras!

Candidates should be aware that Moderna currently maintains a policy requiring all US-based employees to be fully vaccinated against COVID-19 and receive a booster shot once eligible. Newly hired employees must be vaccinated and boosted prior to their employment start date. Moderna is an equal opportunity employer and will provide a reasonable accommodation to those unable to be vaccinated or receive a booster where it is not an undue hardship to the company to do so as provided under federal, state, and local law.

About Moderna

In over 10 years since its inception, Moderna has transformed from a research-stage company advancing programs in the field of messenger RNA (mRNA), to an enterprise with a diverse clinical portfolio of vaccines and therapeutics across seven modalities, a broad intellectual property portfolio in areas including mRNA and lipid nanoparticle formulation, and an integrated manufacturing plant that allows for rapid clinical and commercial production at scale. Moderna maintains alliances with a broad range of domestic and overseas government and commercial collaborators, which has allowed for the pursuit of both groundbreaking science and rapid scaling of manufacturing. Most recently, Moderna's capabilities have come together to allow the authorized use and approval of one of the earliest and most effective vaccines against the COVID-19 pandemic.

Moderna's mRNA platform builds on continuous advances in basic and applied mRNA science, delivery technology and manufacturing, and has allowed the development of therapeutics and vaccines for infectious diseases, immuno-oncology, rare diseases, cardiovascular diseases and autoimmune diseases. Moderna has been named a top biopharmaceutical employer by Science for the past seven years. To learn more, visit

Moderna is a smoke-free, alcohol-free and drug-free work environment.

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Moderna will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

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