Executive Director, Immuno-oncology Strategy, Translational Medicine
AstraZeneca

Job Info

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Executive Director, Immuno-oncology Strategy, Translational Medicine

Location: Gaithersburg, US

Are you a highly motivated Leader with expertise in providing strategic leadership for integration of IO Projects?

We are seeking to appoint an Executive Director within Translational Medicine, who has expertise in providing strategic leadership and a passion for Early Oncology, does this describe you?

At AstraZeneca Oncology, we are not afraid to do things differently. Our vision is redefining cancer, redefining our solutions to cancer and restoring patients' lives. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality.

As the Executive Director, Immuno-oncology Strategy Translational Medicine, you will hold a pivotal role within the Oncology, with responsibility for:

Key Responsibilities:

• Provide strategic leadership for integration of IO projects from discovery to the clinic and from the clinic to discovery to provide insights for the next generation of IO agents
• Develop novel methods to identify IO responses and resistance
• Drive the development of IO biomarker strategy and tactics for use across indications and projects by coordination of activities in pathology, computational pathology and omics.
• Implement biospecimen science in clinical trials to improve sample collection, QC and comprehensive analyses
• Build and progress the early IO portfolio by ensuring clinical development leverages translational medicine strategy and makes data driven decisions during the clinical development of the IO portfolio
• Supervise senior staff leading functional teams in TM
• Develop strong relationships with the senior scientific and other (eg, tumor councils and business development) staff to define, articulate and implement AstraZeneca's scientific vision and strategy
• Align research and early development functions with AstraZeneca's corporate mission, vision and business strategy
• Develop and apply in-depth knowledge of therapeutic areas, emerging relevant preclinical and clinical research, product and competitive landscapes including current treatment strategies, current and potential competitors, and new therapeutic developments
• Build and maintain strong relationships with opinion leaders, collaborators, scientific advisors, alliance partners and patient advocacy groups in order to help drive the scientific communications program and to ensure that team meets scientific and business objectives
• Represent TM and early development functions at Governance and external programs reviews
• Ensure the integration of expertise/findings from discovery research, nonclinical and clinical groups while facilitating broader discussion with groups such as regulatory, process development, market research, business development and legal
• Work closely with regulatory, program management, clinical to formulate regulatory strategy, engage global health agencies and generate approvable BLAs and NDAs.
• Implement value-based, data-driven approaches to managing and prioritizing the research and early development pipeline and portfolio
• Support early clinical PoC and late clinical development, registration

Experience and Required Skills:

• PhD or MD or DVM is required.
• A minimum of 15 years of relevant experience
• The ability to travel (30% of time)
• Ability to align with rigorous scientific methodology standards and present findings for peer review
• Capability to constructively facilitate debate across deep technical and broad strategic issues and develop alternative options
• Ability to create an environment where imaginative and constructive dialog can flourish, conflict is well-managed and complex issues are driven to full resolution
• The ability to attract, retain, manage, coach, and mentor scientific staff
• Extensive experience designing, running, and managing multiple research and early development programs simultaneously
• Comprehensive understanding and ability to articulate the drug development process in all phases of testing so that drug candidates are critically evaluated
• Strong communication and presentation skills are essential and includes: summarization, interpretation, and communication of results and implications of research and early development in order to provide clear recommendations to executive management, alliance partners and regulatory authorities.

This position is located in Gaithersburg, MD

The AstraZeneca Gaithersburg campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This green, sustainable, modern, vibrant scientific campus is where we host some of the most cutting-edge technology and lab spaces. Newly designed, state of the art research spaces and open seating floor plans are just a couple of ways we work cross functionally and collaboratively.

The Gaithersburg campus also provides an award winning café, free garage parking with electric car charging stations, bike racks, free fitness center to include classed and personal training game rooms, outdoor patio, bocce ball court, arcade games and game tables, recharge Pod's, library, walking trails, onsite dry cleaning pickup, haircutting service, health and wellness center, starbucks café, and much more!

So, what's next?

Are you already envisioning yourself joining our team Good, because we can't wait to hear from you!

If you are inspired by the possibilities, don't hesitate in submitting an application today!

Closing date: 10th June 2022

Competitive remuneration and flexible benefits apply!

Where can I find out more?

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Next Steps - Apply today!

To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience - Alternatively, If you know someone who would compliment this role, please share this posting with them!

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