Associate Scientist/Scientist

Gaithersburg, Maryland

Posted in Pharmaceuticals

This job has expired.

Job Info

Associate Scientist/Scientist

Do you have a passion for Science? Would you like to apply your expertise to impact a company that follows the science and turns ideas into life changing medicines? Then AstraZeneca might be the place for you!

At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you're our kind of person.

About AstraZeneca in Gaithersburg, MD:

Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world. This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most groundbreaking technology and lab spaces, all designed to inspire collaboration and cross-functional science. We believe employees benefit from being challenged and inspired at work. We are dedicated to creating a culture of inclusion and collaboration.

The Gaithersburg site offers a variety of amenities to help boost productivity and help keep our employees happy and healthy. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center. This is where you'll find newly-designed, activity-based work spaces to suit a variety of working styles while growing collaboration between teams.

Summary of the group:

Cell Culture Fermentation Sciences (CCFS) designs, develops, optimizes and validates cell culture and fermentation processes for a wide range of biological products. The team generates optimal cell lines and is also responsible for technology transfers into manufacturing. High throughput scale-down models are employed to develop media and processes to support production. The team has occupied a leadership position in industry in terms of antibody productivity and incorporates the latest developments in automation and analytics into its work.

Main Duties & Responsibilities:

This Associate Scientist role is responsible for the development and optimization of upstream biological production processes, either for the purpose of protein expression or viral vector production. Major duties and responsibilities include:

  • Develop robust upstream manufacturing processes, including cell expansion development for various host cells lines and designing and executing experiments in shake flasks or small-scale bioreactors (AMBR15/AMBR250 and 3L) to develop and optimize process performance for viral vectors or recombinant proteins
  • Generate upstream material to support the cross-functional development of pipeline assets
  • Make detailed observations, analyze data, interpret results, and exercise appropriate technical discretion in the design, execution, and interpretation of experimental results in an independent manner.
  • Preparation of technical reports, experimental protocols, and technical summaries for presentation as well as participation in the technology transfer of processes into cGMP production facilities
  • Present and discuss experimental results at group and project team meetings
  • Must be able to work in a team-based structure and interface with research and process development departments

Education & Experience Requirements:

Education: BS/MS/PhD in Chemical/Biochemical Engineering, Biotechnology, Biochemistry, Cell Biology, Immunology, Biological Sciences or related field.

Experience: Bachelor's degree and 5+ years or Master's degree and 2+ years or PhD with 0+ years of relevant industry or academia experience

Required Skills:
  • Possess practical knowledge of process engineering and biopharmaceutical operations
  • Good foundation in mammalian cell culture techniques and solid aseptic technique
  • "Hands-on" working experience with fermenters/bioreactors in the development and optimization of viral vector platforms/AAV/recombinant proteins
  • Understanding of safety, health & environment (SHE) and relevant standards
  • Must be able to generate complete and concise written documentation and presentations with little supervision and be able to present data in a clear and concise manner to various teams
  • Excellent communication skills, with the ability to collaborate with colleagues in a cross-functional, fast paced team environment

Desired Skills:
  • Molecular biology skills such as recombinant DNA techniques and mammalian cell transfection
  • Use of DOE (design of experiments) approach in process development and optimization, including use of statistical programs such as JMP
  • Experience and/or working knowledge of recovery and clarification techniques
  • Experience in single-use and perfusion technology

Why AstraZeneca?

At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognizing their potential. Join us on our journey of building a new kind of organization to reset expectations of what a bio-pharmaceutical company can be. This means we're opening new ways to work, pioneering cutting edge methods and bringing unexpected teams together. Interested? Come and join our journey.

So, what's next?

Are you ready to bring new ideas and fresh thinking to the table? Brilliant! We have one seat available, and we hope it's yours.

Where can I find out more?

Check out our landing page for more information on our BPD group:

Our Social Media:

Follow AstraZeneca on LinkedIn

Follow AstraZeneca on Facebook

Follow AstraZeneca on Instagram

This job has expired.

More Pharmaceuticals jobs

Akorn 2
Amityville, New York
Posted about 7 hours ago

Akorn 2
Amityville, New York
Posted about 7 hours ago

Bedminster, New Jersey
Posted about 6 hours ago

Improve Job Search

Subscribe to job alerts and add your resume to our resume database for employers!

Sign up now